The fourth issue of SuperF*ckers (#279) almost turned out completely differently than the version you know and love.   The first page I drew, I had Omnizod (née Percy) returning to earth:

Then I changed my mind and decided it wasn’t yet time for a return.  As you can see, this version of Omnizod is very different than the one that ended up in the actual issue, instead of a floating flaming skull, it’s Percy’s tattered body with a glowing orb of energy where his head should be.  The flaming skull is way better.  Also in this page is my favorite SuperF*cker, Computer Fist… who ended up not being in the issue at all.  In the previously published issue, he was kicked off the team and I was going to draw him hanging around waiting to be let back in.  It’s funny, ’cause the story could go in a million different directions, my head is swarming with buzzing ideas for directions to take the story in, so many that I’m never quite sure exactly what is going to happen.